68218-52-0Relevant academic research and scientific papers
FACILE SYNTHESIS OF N-SUBSTITUTED 1H-AZEPINE DERIVATIVES
Ayyangar, Nagaraj R.,Bambal, Ramesh B.,Lugade, Ananda G.
, p. 77 - 82 (2007/10/02)
The facile synthesis of N-sulphonyl and N-ethoxycarbonyl substituted 1H-azepines in high yields by the pressure-induced sulphonylnitrene insertion reaction or, in anhydrous solvents, the 1,3-dipolar azide addition reaction with aromatic substrates containing electron-withdrawing substituents (e.g. dimethyl terephthalate) are described.The probable sequences of reactions involved in the two cases have been indicated.
