68234-97-9Relevant academic research and scientific papers
Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
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Page/Page column 22, (2008/06/13)
Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including huma
Lewis Acid-mediated α-tert-Alkylation of Carboxylic Acids and Carboxylic Esters
Reetz, Manfred T.,Schwellnus, Konrad,Huebner, Friedhelm,Massa, Werner,Schmidt, Roland E.
, p. 3708 - 3724 (2007/10/02)
Carboxylic acids and carboxylic esters can be α-tert-alkylated via the corresponding ketene silyl acetals 2 and 4 using tertiary alkyl halides or acetates in the presence of ZnCl2.The method is successful even if the products are sterically strained due t
