682356-45-2

Upstream product

• 50612-99-2 methyl 2-bromo-2-(4-methoxyphenyl)acetate 
• 682356-51-0 [5-methoxy-2-(4-methoxy-phenyl)-1,3-dioxo-indan-2-yl]-(4-methoxy-phenyl)-acetic acid methyl ester 
• 42223-08-5 2-(4-methoxyphenyl)-5-methoxy-1,3-indandione 

Relevant academic research and scientific papers

Comparison of 2-phenylspiroindenes and 2-phenylspiroindenediones as estrogen receptor ligands - Modeling and binding data don't agree!

A series of 2-phenylspiroindenediones was prepared. The spiroindenediones were found to be less active than the corresponding spiroindenes as estrogen receptor ligands and failed to demonstrate the receptor subtype selectivity that had been anticipated from molecular modeling.