68240-62-0

Usage

Uses

Used in Pharmaceutical Research:
1-((4-bromophenyl)(phenyl)methyl)piperazine is used as a research chemical for studying its interactions with serotonin and dopamine receptors in the central nervous system. This application is crucial for understanding its potential pharmacological effects and possible therapeutic uses in the treatment of various neurological and psychiatric disorders.
Used in Psychoactive Substance Research:
1-((4-bromophenyl)(phenyl)methyl)piperazine is also used as a research chemical in the study of its potential as a psychoactive substance. This application aims to explore its effects on human cognition, mood, and behavior, as well as its potential for recreational use. However, it is important to note that the safety and efficacy of 1-((4-bromophenyl)(phenyl)methyl)piperazine for such purposes have not been well established, and it is not approved for human consumption.
Used in Drug Development:
In the pharmaceutical industry, 1-((4-bromophenyl)(phenyl)methyl)piperazine may be used as a starting point or a structural component in the development of new drugs targeting the central nervous system. Its interactions with serotonin and dopamine receptors make it a valuable compound for researchers to study and potentially modify for the creation of novel therapeutic agents.
It is important to emphasize that the use of 1-((4-bromophenyl)(phenyl)methyl)piperazine should be limited to controlled research settings, as its safety and efficacy for human consumption have not been established. Further studies are necessary to fully understand its potential applications and risks.

Upstream product

• 110-85-0 piperazine 
• 13391-38-3 4-bromo-benzhydryl chloride 
• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 1122-91-4 4-bromo-benzaldehyde 
• 100-58-3 phenylmagnesium bromide 
• 18066-89-2 1-bromo-4-<(bromophenyl)methyl>benzene 
• 29334-16-5 phenyl(4-bromophenyl)methanol 

Relevant academic research and scientific papers

Synthesis of Allocolchicine Conjugates with a Cetirizine Analog

Conjugates of allocolchicine and a cetirizine analog have been synthesized as potential anti-inflammatory and anti-allergic drugs.

Synthesis and Anticancer Activity of 1-(1H -Indol-3-yl)-2-(4-diarylmethylpiperazine-1-yl)ethane-1,2-dione Derivatives

Several new 1-(4-diarylmethylpiperazine-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione derivatives were synthesized by acylation of 1-diarylmethylpiperazine with 2-(1H-indol-3-yl)-2-oxoacetyl chloride. Their structures were confirmed by 1H NMR, IR, mass spectra, and elemental analysis. These compounds were further evaluated for their anticancer activity, and most of them were found to have moderate-to-potent antiproliferative activities against Hela, A-549, and ECA-109 cancer cell lines in vitro.

Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidines: A novel class of potent enterovirus inhibitors

A series of pyrazolo[3,4-d]pyrimidines were synthesized and their antiviral activity was evaluated in a plaque reduction assay. It is very interesting that this class of compounds provide remarkable evidence that they are very specific for human enteroviruses, in particular, coxsackieviruses. Some derivatives proved to be highly effective in inhibiting enterovirus replication at nanomolar concentrations. SAR studies revealed that the phenyl group at the N-1 position and the hydrophobic diarylmethyl group at the piperazine largely influenced the in vitro antienteroviral activity of this new class of potent antiviral agents. It was found that the pyrazolo[3,4-d]pyrimidines with a thiophene substituent, such as compounds 20-24, in general exhibited high activity against coxsackievirus B3 (IC50=0.063-0.089μM) and moderate activity against enterovirus 71 (IC50=0.32-0.65μM) with no apparent cytotoxic effect toward RD (rhabdomyosarcoma) cell lines (CC5025μ M).