68277-91-8

Upstream product

• 696-62-8 para-iodoanisole 
• 90-94-8 bis(p-dimethylaminophenyl)methanone 
• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 
• 1360570-15-5 C₂₉H₃₉N₂OSi⁽¹⁺⁾ 
• 1369203-59-7 C₂₉H₄₀N₂O₂Si 
• 106-41-2 4-bromo-phenol 
• 1442689-45-3 C₂₄H₂₅N₃O 

Relevant academic research and scientific papers

Selective and sensitive chromogenic detection of cyanide and HCN in solution and in gas phase

Two triphenylmethane based chemodosimeters for selective and chromogenic sensing of cyanide anions in aqueous environments and of hydrogen cyanide in gas phase were prepared and studied.

Selective detection of nerve agent simulants by using triarylmethanol-based chromogenic chemodosimeters

A family of triarylcarbinols 1-11 has been synthesised, and the chromogenic behaviour of the members in the presence of nerve-agent simulants diethylcyanophosphonate (DCNP) and diisopropylfluorophosphate (DFP) in acetonitrile and in buffered mixed water/acetonitrile solutions has been investigated. Hydrophobic polyethylene oxide films of these compounds have been prepared. Some of these triarylcarbinols act as OFF/ON chemodosimeters for the nerve agent simulants. The sensing mechanism includes phosphorylation of the hydroxyl group in the triarylcarbinol derivatives, followed by a dephosphatation reaction induced by the electron-donor groups present in the structure. The existence of additional tert-butyldimethylsilyl ether groups in compounds 2 and 3 permits these reagents to act as double probes by allowing selective signalling of DFP. The reactivity between 1 and 4-6 with DFP and DCNP in acetonitrile or water/acetonitrile solutions under pseudo first-order kinetic conditions was studied to determine rate constants (k) and the half-life times (t1/2) for the corresponding reactions. Films containing compound 2 were used to detect simulants both in solution and in the vapour phase. Finally, a logic device was designed that incorporated compounds 2, 14, and 15 that allowed detection of DFP (a Sarin and Soman simulant) and DCNP (a Tabun simulant), even in the presence of possible interferents such as acids. Triarylmethanol derivatives as visual OFF/ON chromodosimeters of nerve-agent simulants (DCNP and DFP), even in water/acetonitrile (3:1 v/v) solutions, were investigated. The developed compounds were able to act as double probe systems and allowed the selective signalling of DFP. Films of compound 2 were used to detect the simulants in solution and in the vapour phase. Copyright

A molecular probe for the highly selective chromogenic detection of DFP, a mimic of sarin and soman nerve agents

Lethal-weapon visualization: A novel triarylmethanol derivative, which is able to colorimetrically distinguish diisopropylfluorophosphate (DFP; a mimic of Sarin and Soman) from other nerve-agent simulants, is reported (see picture). This probe was designed to contain two reactive sites: an OH group that provides a suitable reactive group for nerve agents and a tert-butyldimethylsilylether moiety that is able to react with fluoride, which is a specific byproduct of the phosphorylation of OH by DFP.