682805-38-5Relevant academic research and scientific papers
A One-Pot Synthesis of Coumarins from Dipotassium O-Methoxybenzylidenemalonates
Hormi, Osmo E.O.,Peltonen, Carita,Bergstroem, Riitta
, p. 219 - 222 (2007/10/02)
o-Methoxybenzylidenemalonates 1, which are available from o-methoxybenzaldehydes and diethylmalonate, were hydrolysed to the dipotassium malonates 2.Treatment of the salts 2 with trifluoroacetic acid-trifluoroacetic anhydride gave the title coumarins by a demethylative ring-closure reaction in 60-80percent yield.
