68281-76-5Relevant academic research and scientific papers
Bicyclic Heterocycles with Nitrogen at the Ring Junction. Part 2. Application of the Dakin-West Reaction to the Synthesis of Imidazo-1,2,4-triazin-4(3H)-ones
Charles, Isabel,Latham, David W. S.,Hartley, David,Oxford, Alexander W.,Scopes, David I. C.
, p. 1139 - 1146 (2007/10/02)
A series of novel acylamino α-keto-esters (4) have been prepared via a Dakin-West reaction of acylated α-amino-acids and ethyl oxalyl chloride.Their use in a general synthesis of imidazo-1,2,4-triazin-4(3H)-ones (7) is described.The conversion of t
