68290-36-8 Usage
Uses
Used in Pharmaceutical Industry:
2-(3,4-DIFLUOROPHENYL)INDOLE is used as a potential drug candidate for its potential biological activities, including anti-inflammatory, anticancer, and antimicrobial properties. The 3,4-difluorophenyl substituent may enhance the compound's therapeutic efficacy and selectivity, making it a valuable asset in the development of new pharmaceutical agents.
Used in Medicinal Chemistry Research:
2-(3,4-DIFLUOROPHENYL)INDOLE serves as a subject of study in medicinal chemistry research, where its unique chemical and biological properties are explored for drug development purposes. 2-(3,4-DIFLUOROPHENYL)INDOLE's structure and activity may provide insights into the design of novel therapeutic agents with improved pharmacological profiles.
Used in Drug Discovery and Development:
2-(3,4-DIFLUOROPHENYL)INDOLE is utilized in drug discovery and development processes to identify new pharmaceutical agents with therapeutic potential. Its indole-based structure and the presence of the 3,4-difluorophenyl group offer a foundation for the design and synthesis of novel compounds with enhanced biological activities and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 68290-36-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,2,9 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 68290-36:
(7*6)+(6*8)+(5*2)+(4*9)+(3*0)+(2*3)+(1*6)=148
148 % 10 = 8
So 68290-36-8 is a valid CAS Registry Number.
68290-36-8Relevant academic research and scientific papers
Synthesis of 2-Substituted Indoles through Visible Light-Induced Photocatalytic Cyclizations of Styryl Azides
Xia, Xu-Dong,Xuan, Jun,Wang, Qiang,Lu, Liang-Qiu,Chen, Jia-Rong,Xiao, Wen-Jing
, p. 2807 - 2812 (2016/02/18)
A visible light-induced photocatalytic intramolecular cyclization of styryl azides has been developed in the presence of the ruthenium complex Ru(bpy)3Cl2 (0.5 mol%) as photocatalyst at room temperature. The present photocatalytic strategy features operational simplicity as well as high functional group tolerance, and provides a facile access to various 2-substituted N-free indoles in good to excellent yields. Importantly, the present process can employ sunlight as the light source to afford the corresponding products without loss of reaction efficiency.
Copper catalysed domino decarboxylative cross coupling-cyclisation reactions: Synthesis of 2-arylindoles
Ponpandian, Thanasekaran,Muthusubramanian, Shanmugam
, p. 4248 - 4252 (2012/08/28)
The efficient synthesis of 2-arylindoles and 6H-isoindolo[2,1-a]indol-6-one through copper catalysed domino sp-sp2 decarboxylative cross-coupling and subsequent cyclisation reactions of arylpropiolic acids with 2-iodotrifluoroacetanilide has been described. This methodology also demonstrates that indolo[1,2-c]quinazolin-6(5H)-one can be obtained with the elimination of trifluoromethyl anion.
