68298-28-2Relevant academic research and scientific papers
Cyclopropenation of alkylidene carbenes derived from α-silyl ketones
Li, Jingwei,Sun, Chunrui,Lee, Daesung
supporting information; experimental part, p. 6640 - 6641 (2010/07/04)
A new cyclopropanation reaction involving Cα-Si bond insertion of alkylidene carbenes derived from α-silyl ketones has been developed. This unprecedented alkylidene carbene reactivity features excellent selectivity for insertion into Cα-Si bonds rather than insertion into Cγ-H bonds or addition to,δ-double or -triple bonds. The selectivity trend clearly indicates that the α-oxygen in the tether significantly promotes Cγ-H insertion, although the Cα-Si bond insertion still competes effectively.
