68301-79-1Relevant academic research and scientific papers
Studies on the Chemical Reactions of Some 3-Substituted-6,8-dimethylchromones with Nucleophilic Reagents
Ibrahim, Magdy A.,Badran, Al-Shimaa,El-Gohary, Nasser M.,Hashiem, Salsabeel H.
, p. 2315 - 2324 (2018)
A variety of 3-substituted-6,8-dimethylchromones have been synthesized and characterized. The chemical reactivity of 3-substituted-6,8-dimethylchromones was studied towards some nucleophiles, namely, S-benzyldithiocarbazate, o-phenylenediamine, and cyanoacetamide, and a diversity of products were efficiently synthesized. Reactions of 3-substituted-6,8-dimethylchromones (except 3-formyl-6,8-dimethylchromone), with nucleophilic reagents, usually proceed through nucleophilic attack at C-2 position followed by different types of heterocyclization depending on the functional group present at C-3 position. Structures of the newly synthesized products have been established based on elemental analysis and spectral data.
SYNTHESIS OF 3-SUBSTITUTED-5-OXO-5H-BENZOPYRANOPYRIDINE DERIVATIVES
Ishiguro, Toshihiro,Ukawa, Kiyoshi,Sugihara, Hirosada,Nohara, Akira
, p. 733 - 740 (2007/10/02)
3-Cyano-. 3-alkoxycarbonyl-, and 3-formyl-5-oxo-5H-benzopyranopyridine dervatives were prepared by reactions of 2-amino-4-oxo-4H-1-benzopyran-3-carboxaldehydes 1 with acetylene derivatives (methods A-C) or with reactive methylene compounds (methods D-E) and also by catalytic hydrogenation of 2-chloro-5-oxo-5H-benzopyranopyridine-3-carbonitriles 12 (method F).
