68303-68-4

Upstream product

• 10334-26-6 (R)-camphorquinone 
• 591-51-5 phenyllithium 
• 108-86-1 bromobenzene 

Downstream Products

• 128425-65-0 (+)-(1R,2S,3R,4S)-2-endo,3-endo-diphenyl-2,3-epoxy bornane 
• 128425-66-1 Dimethyl-((1R,2S,4S,6S,7S)-1,10,10-trimethyl-2,6-diphenyl-3,5-dioxa-tricyclo[5.2.1.0^2,6]dec-4-yl)-amine 

Relevant academic research and scientific papers

Synthesis of camphor based chiral crown ethers and their interactions with amino acid derivatives

Three camphor based crown ethers have been prepared, starting from (-)-(1R)-camphorquinone, in which 2- and 3-endo-substituents are used to regulate the availability of the endo-18-crown-6 face for binding organic guests and the bridge head methyl group is available to impart enantioselectivity at the exo-face.The stereochemistry of the key intermediate 2-endo-3-endo-dimethyl bornane-2,3-diol (6) has been confirmed by a single crystal X-ray structure determination.Interactions between these crowns and antipodal phenylglycine salts have been probed using NMR and modelling techniques.