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68321-04-0

2-(4-phenoxyphenyl)-1H-benzo[d]imidazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 68321-04-0 Structure

  • Basic information

    1. Product Name: 2-(4-phenoxyphenyl)-1H-benzo[d]imidazole
    2. Synonyms: 2-(4-phenoxyphenyl)-1H-benzo[d]imidazole
    3. CAS NO:68321-04-0
    4. Molecular Formula:
    5. Molecular Weight: 286.333
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 68321-04-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(4-phenoxyphenyl)-1H-benzo[d]imidazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(4-phenoxyphenyl)-1H-benzo[d]imidazole(68321-04-0)
    11. EPA Substance Registry System: 2-(4-phenoxyphenyl)-1H-benzo[d]imidazole(68321-04-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 68321-04-0(Hazardous Substances Data)

68321-04-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 68321-04-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,3,2 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 68321-04:
(7*6)+(6*8)+(5*3)+(4*2)+(3*1)+(2*0)+(1*4)=120
120 % 10 = 0
So 68321-04-0 is a valid CAS Registry Number.

68321-04-0Relevant articles and documents

Photochemical Synthesis of Benzimidazoles from Diamines and Aldehydes

Skolia, Elpida,Apostolopoulou, Mary K.,Nikitas, Nikolaos F.,Kokotos, Christoforos G.

, p. 422 - 428 (2021)

An efficient, green, cheap, and metal-free photochemical protocol for the synthesis of benzimidazoles has been developed. 2,2-Dimethoxy-2-phenylacetophenone was employed as the photoinitiator and CFL lamps were used as the light source, leading to the cyc

2-ARYLBENZIMIDAZOLES AS PPARGC1A ACTIVATORS FOR TREATING NEURODEGENERATIVE DISEASES

-

Paragraph 85; 90, (2020/03/02)

A genus of compounds encompassed by formula (III) and their use is disclosed: Formula (III). The compounds activate Ppargc1a and, as a consequence, are useful for treating a variety of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, Huntington's disease, frontotemporal degeneration, dementia with Lewy bodies, motor neuron diseases, and a demyelinating disease.

Synthesis and SAR investigations of novel 2-arylbenzimidazole derivatives as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists

Lim, Chae Jo,Kim, Nakjeong,Lee, Eun Kyoung,Lee, Byung Ho,Oh, Kwang-Seok,Yoo, Sung-Eun,Yi, Kyu Yang

supporting information; experimental part, p. 2309 - 2312 (2011/05/15)

Compounds containing 2-arybenzimidazole ring systems linked to arylpiperidines were synthesized and evaluated as MCH-R1 antagonists. The results of structure-activity relationship studies led to the identification of compound 4c as a potent MCH-R1 antagonist (IC50 = 1 nM). This compound also has good metabolic stability, and favorable pharmacokinetic and brain penetration properties. However 4c was found to be potent inhibitor of the hERG potassium channel.

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