68321-98-2 Usage
Class
Heterocyclic compounds
Structure
Contains a quinazoline ring
Pharmacological applications
Has shown promising activity as an inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell signaling
Potential use in
Cancer therapy and treatment of various neurodegenerative diseases
Other properties
Demonstrated anti-inflammatory and immunomodulatory properties
Current status
Further research is ongoing to explore the full pharmacological potential of DPQ.
Check Digit Verification of cas no
The CAS Registry Mumber 68321-98-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,3,2 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 68321-98:
(7*6)+(6*8)+(5*3)+(4*2)+(3*1)+(2*9)+(1*8)=142
142 % 10 = 2
So 68321-98-2 is a valid CAS Registry Number.
68321-98-2Relevant academic research and scientific papers
Reaction of anthranilic acid amides with cyclic anhydrides
Shemchuk,Chernykh,Krys'kiv
, p. 382 - 387 (2007/10/03)
Anthranilic acid amide reacts with cyclic anhydrides to give the corresponding N-acyl derivatives at the amino group, while analogous reactions of o-aminobenzohydroxamic acid lead to formation of 3-hydroxyquinazolin-4-ones under mild conditions. N-Acyl derivatives of anthranilic acid amide undergo intramolecular cyclization to imides on microwave irradiation or on melting, and their treatment with acetic anhydride in the presence of sodium acetate on heating yields quinazolin-4-ones. Pleiades Publishing, Inc., 2006.
