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6-(1,4-Diazepan-1-yl)nicotinonitrile, a heterocyclic compound with the molecular formula C12H15N3, belongs to the class of nicotinonitriles. It features a seven-membered diazepane ring and a pyridine ring with a nitrile group. This chemical compound has potential pharmaceutical applications due to its ability to modulate the central nervous system, primarily by targeting the GABA-A receptor.

683274-59-1

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683274-59-1 Usage

Uses

Used in Pharmaceutical Industry:
6-(1,4-Diazepan-1-yl)nicotinonitrile is used as a pharmaceutical agent for its potential therapeutic effects on various neurological disorders. It targets the GABA-A receptor, which plays a crucial role in reducing neuronal excitability and promoting relaxation.
Used in Treatment of Anxiety:
6-(1,4-Diazepan-1-yl)nicotinonitrile is used as an anxiolytic agent for its potential to alleviate anxiety symptoms. By modulating the GABA-A receptor, it helps in reducing anxiety levels and promoting a sense of calmness.
Used in Treatment of Epilepsy:
6-(1,4-Diazepan-1-yl)nicotinonitrile is used as an anticonvulsant and antiepileptic agent for its potential to control seizures and prevent the onset of epilepsy. Its action on the GABA-A receptor helps in stabilizing neuronal activity and preventing abnormal electrical discharges in the brain.
Used in Treatment of Insomnia:
6-(1,4-Diazepan-1-yl)nicotinonitrile is used as a sleep aid for its potential to improve sleep quality and duration. By targeting the GABA-A receptor, it helps in promoting relaxation and facilitating the onset of sleep, thus benefiting individuals suffering from insomnia.

Check Digit Verification of cas no

The CAS Registry Mumber 683274-59-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,3,2,7 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 683274-59:
(8*6)+(7*8)+(6*3)+(5*2)+(4*7)+(3*4)+(2*5)+(1*9)=191
191 % 10 = 1
So 683274-59-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N4/c12-8-10-2-3-11(14-9-10)15-6-1-4-13-5-7-15/h2-3,9,13H,1,4-7H2

683274-59-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(1,4-diazepan-1-yl)pyridine-3-carbonitrile

1.2 Other means of identification

Product number -
Other names 5-(1,4-diazepan-1-yl)picolinonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:683274-59-1 SDS

683274-59-1Downstream Products

683274-59-1Relevant academic research and scientific papers

PYRIDAZINONES AS PARP7 INHIBITORS

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, (2019/11/11)

The present invention relates to pyridazinones and related compounds which are inhibitors of PARP7 and are useful in the treatment of cancer.

TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

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Page/Page column 74, (2009/01/24)

A triazole derivative of formula 1 or a pharmaceutically acceptable salt, hydrate, solvate or isomer thereof is superior to the conventional antifungal drugs in antifungal activity against a wide spectrum of pathogenic fungi, and has advantageously low toxicity.

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