68374-20-9

Basic information

• Product Name: 2,2-dimethyl-17β-methoxy-5α-androstan-3-one
• Synonyms: 2,2-dimethyl-17β-methoxy-5α-androstan-3-one
• CAS NO: 68374-20-9
• Molecular Weight: 332.527
• Mol File: 68374-20-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-dimethyl-17β-methoxy-5α-androstan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-17β-methoxy-5α-androstan-3-one(68374-20-9)
• EPA Substance Registry System: 2,2-dimethyl-17β-methoxy-5α-androstan-3-one(68374-20-9)

Safety Data

• Hazardous Substances Data: 68374-20-9(Hazardous Substances Data)

Upstream product

• 2639-53-4 (5α,17β)-androst-2-en-17-ol 

Relevant articles and documents

STEREOSELECTIVE REDUCTION OF C-2 SUBSTITUTED STEROID C-3 KETONES WITH LITHIUM TRIS-(R,S-1,2-DIMETHYLPROPYL)-BOROHYDRIDE AND SODIUM BOROHYDRIDE

The effect of C-2 substitution on the stereoselective reduction of steroid C-3 ketones with lithium tris(R,S-1,2-dimethylpropyl)-borohydride and sodium borohydride was investigated.The C-2 mono- and di-substituted chloro and methyl derivatives were predominantly reduced to one of the epimeric alcohols.The 2α-chloro and 2α-methyl derivatives of 17β-acetoxy-5α-androstan-3-one undergo stereoselective reduction with lithium tris (R,S-1,2-dimethylpropyl)-borohydride to the axial (3α) alcohol as observed in the unsubstituted compound, whereas sodium borohydride gives predominantly the equatorial (3β) alcohol.The 2β-chloro, 2β-methyl, 2,2-dichloro, and 2,2-dimethyl derivatives are reduced predominantly to the equatorial (3β) alcohol by both reagents.