683805-44-9

Basic information

• Product Name: {6-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-2,2-dimethyl-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-cyclopenta[b]phenanthren-5-yl}-methanol
• CAS NO: 683805-44-9
• Molecular Weight: 558.744
• Mol File: 683805-44-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {6-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-2,2-dimethyl-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-cyclopenta[b]phenanthren-5-yl}-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: {6-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-2,2-dimethyl-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-cyclopenta[b]phenanthren-5-yl}-methanol(683805-44-9)
• EPA Substance Registry System: {6-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-2,2-dimethyl-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-cyclopenta[b]phenanthren-5-yl}-methanol(683805-44-9)

Safety Data

• Hazardous Substances Data: 683805-44-9(Hazardous Substances Data)

Upstream product

• 118356-07-3 4'-O-tert-butyldimethylsilanyl-4'-O-demethyl-4-epipodophyllotoxin 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 6559-91-7 4'-demethylepipodophyllotoxin 
• 77-76-9 2,2-dimethoxy-propane 
• 683805-43-8 8-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-6,7-bis-hydroxymethyl-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxol-5-ol 

Downstream Products

• 683805-47-2 {6-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-2,2-dimethyl-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-cyclopenta[b]phenanthren-5-yl}-acetonitrile 
• 683805-46-1 2-[(4aR,5R,6R,11bS)-6-(4-Hydroxy-3,5-dimethoxy-phenyl)-2,2-dimethyl-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-cyclopenta[b]phenanthren-5-yl]-acetamide 
• 683805-45-0 [(4aR,5R,6R,11bS)-6-(4-Hydroxy-3,5-dimethoxy-phenyl)-2,2-dimethyl-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-cyclopenta[b]phenanthren-5-yl]-acetonitrile 

Relevant articles and documents

Synthesis of podophyllotoxin analogues: δ-lactone-containing picropodophyllin, podophyllotoxin and 4′-demethyl-epipodophyllotoxin derivatives

Non-epimerizable cis and trans δ-lactone analogues of podophyllotoxin have been prepared. Thus the synthesis of the cis isomer 4 has been achieved in 8 steps and 4% overall yield from podophyllotoxin 1 via the reduction of the γ lactone ring into the tran