68395-93-7Relevant academic research and scientific papers
Stereo- and Regioselective Cu-Catalyzed Hydroboration of Alkynyl Chalcogenoethers
de Oliveira, Isadora M.,Esteves, Henrique A.,Darbem, Mariana P.,Sartorelli, Arthur,Correra, Thiago C.,Rodrigues-Oliveira, André F.,Pimenta, Daniel C.,Zukerman-Schpector, Julio,Manarin, Flávia,Stefani, Hélio A.
, p. 3545 - 3552 (2020/06/02)
A mild stereo- and regioselective Cu-catalyzed hydroboration method for the synthesis of (Z)-seleno-alkenyl boronates and (Z)-thio-alkenylboronates from internal alkynes in the presence of commercially available B2pin2 is presented. This highly selective transformation relies on the use of N-heterocyclic carbene (NHC) complex IPrCuCl as the active catalytic species. We also explore the functionalization of the alkenylboronates obtained via oxidation to give α-chalcogeno ketones, useful building blocks for the synthesis of more complex chalcogen-containing molecules.
