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MOPSO, also known as 3-(N-Morpholino)propanesulfonic acid, is a zwitterionic buffer that operates within the 6-7 pH range. It is a second-generation "Good's" buffer, characterized by its improved solubility compared to traditional "Good's" buffers. MOPSO is a white crystalline powder with a pKa value of 6.9, making it suitable for buffer formulations that require a pH slightly below physiological levels. It is considered non-toxic to culture cell lines and offers high-solution clarity.

68399-77-9

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68399-77-9 Usage

Uses

Used in Pharmaceutical Synthesis:
MOPSO is used as a buffer in pharmaceutical synthesis for maintaining a stable environment in solution, which is crucial for various chemical reactions and processes.
Used in Cell Culture Media:
MOPSO is used as a biological buffer in cell culture media to provide a stable pH environment slightly below physiological levels, ensuring optimal cell growth and function.
Used in Biopharmaceutical Buffer Formulations:
MOPSO is used as a buffer in both upstream and downstream biopharmaceutical processes, such as protein purification and formulation development, to maintain a stable pH environment that is essential for the stability and activity of biopharmaceutical products.
Used in Diagnostic Reagents:
MOPSO is used as a buffer in the formulation of diagnostic reagents, providing a stable pH environment that is critical for the accurate and reliable performance of diagnostic tests.

Check Digit Verification of cas no

The CAS Registry Mumber 68399-77-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,3,9 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 68399-77:
(7*6)+(6*8)+(5*3)+(4*9)+(3*9)+(2*7)+(1*7)=189
189 % 10 = 9
So 68399-77-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H15NO5S/c9-7(6-14(10,11)12)5-8-1-3-13-4-2-8/h7,9H,1-6H2,(H,10,11,12)/t7-/m1/s1

68399-77-9 Well-known Company Product Price

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  • (Code)Product description
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  • TCI America

  • (H0671)  2-Hydroxy-3-morpholinopropanesulfonic Acid  >98.0%(T)

  • 68399-77-9

  • 25g

  • 160.00CNY

  • Detail
  • Alfa Aesar

  • (44135)  MOPSO, 98%   

  • 68399-77-9

  • 10g

  • 71.0CNY

  • Detail
  • Alfa Aesar

  • (44135)  MOPSO, 98%   

  • 68399-77-9

  • 50g

  • 272.0CNY

  • Detail
  • Alfa Aesar

  • (44135)  MOPSO, 98%   

  • 68399-77-9

  • 250g

  • 1360.0CNY

  • Detail
  • Alfa Aesar

  • (44135)  MOPSO, 98%   

  • 68399-77-9

  • 1kg

  • 5441.0CNY

  • Detail

68399-77-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-3-morpholin-4-ylpropane-1-sulfonic acid

1.2 Other means of identification

Product number -
Other names 2-Hydroxy-3-morpholinopropanesulfonic acid,Free Acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:68399-77-9 SDS

68399-77-9Downstream Products

68399-77-9Relevant academic research and scientific papers

Method for synthesizing 3 - (N - morpholinyl) -2 - hydroxyl propanesulfonic acid without solvent

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Paragraph 0025-0055, (2021/11/10)

The invention relates to a method for synthesizing 3 - (N - morpholinyl) -2 - hydroxyl propanesulfonic acid without a solvent, and belongs to the technical field of organic synthesis. To the method, morpholine and 3 -chloro -2 -hydroxypropanesulfonate are adopted, the reaction is conducted under the condition of no solvent, and 3 - (N - morpholinyl) -2 - hydroxypropanesulfonic acid is obtained after the reaction is finished. Compared with the original 3 - (N - morpholinyl) -2 - hydroxypropanesulfonic acid production process, the raw materials are easily available, the operation is simple, the process yield is high and stable, and the product quality is excellent. The problems that the yield is low and the process is complex in the prior art are solved.

ENHANCING AGENT FOR DETECTION OF ANALYTE IN SPECIMEN, AND METHOD FOR DETECTING ANALYTE IN SPECIMEN

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, (2020/11/30)

Detection rapidly and with high detection intensity is accomplished while blackening is inhibited during silver enhancement to detect an analyte in a specimen. One embodiment of the present invention provides an enhancing agent to be used for silver enhancement in detection of an analyte in a specimen by metal labeling and silver enhancement, the enhancing agent including: (a) a silver-containing compound,(b) a silver ion-reducing agent, and(c) a reaction rate controller, wherein the reaction rate controller (c) is a compound selected from the group consisting of compounds represented by the following formula (I): (wherein: R1, R2 and R3 each independently represent a hydrogen atom or an optionally substituted monovalent aliphatic hydrocarbon group of 1 to 30 carbon atoms, with the proviso that R1, R2 and R3 are not all hydrogen atoms, or R1 and R2 form a 5-membered ring or 6-membered ring and R3 represents a hydrogen atom or an optionally substituted monovalent aliphatic hydrocarbon group of 1 to 30 carbon atoms;X represents a divalent hydrocarbon group of 1 to 3 carbon atoms; andn is an integer of 1 to 3).

3-(N-morpholine)-2-hydroxyl propanesulfonic acid synthesizing technology

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Paragraph 0011; 0012; 0013; 0014, (2017/04/28)

The invention relates to a 3-(N-morpholine)-2-hydroxyl propanesulfonic acid synthesizing technology, and discloses a preparation method of a N-substituted morpholine organic compound. The preparation method comprises the following steps that cyclodehydration is conducted to obtain morpholine, neutralizing, filtering, rectifying and synthesizing are conducted to obtain 3-(N-morpholine)-2-hydroxyl propanesulfonic acid, and chromatography and purification are conducted to obtain the final product. According to the method, reaction conditions are mild, operation is easy and convenient, the safety is high, industrialization is easy to achieve, and the yield is stably 95% or above; in addition, reagents are low in cost and easy to obtain, and therefore obvious cost and technique advantages are achieved.

Stabilizing labeled antibody using amino acids

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, (2011/11/07)

The present invention relates to a method for stabilizing a labeled antibody in a solution, in which the labeled antibody is stabilized by allowing the labeled antibody to be present together with at least one of amino acid and a derivative thereof in the solution.

Amino-hydroxy-alkyl sulfonic acid zwitterions

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, (2008/06/13)

Novel amino-hydroxy-alkylene sulfonic acid zwitterions are described which have the general formulas STR1 wherein A and B are each independently a hydrogen atom, an aliphatic, cycloaliphatic or hydroxyaliphatic group, N is one or two, and R=n is a cyclic radical comprising one or two ring nitrogen atoms, zero or one ring oxygen atoms and the remainder of the ring being carbon atoms, and water soluble salts of said acids. These organo-sulfonic acid compounds are useful as hydrogen ion buffers in biological research and particularly for tissue culture.

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