68401-59-2

Upstream product

• 76-83-5 trityl chloride 
• 64485-82-1 (Z)-ethyl 2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetate 
• 106-96-7 propargyl bromide 
• 66338-99-6 ethyl (Z)-2-hydroxyimino-2-(2-triphenylmethylaminothiazol-4-yl)acetate 

Relevant academic research and scientific papers

Synthesis and antibacterial evaluation against resistant Gram-negative bacteria of monobactams bearing various substituents on oxime residue

Based on the structural characteristics of aztreonam (AZN) and its target PBP3, a series of new monobactam derivatives bearing various substituents on oxime residue were prepared and evaluated for their antibacterial activities against susceptible and res

7-[2-(2-Aminothiazol-4-yl)-2-cyclopentyloxyiminoacetamido]-3-cephem-4-carboxylic acid (synisomer)

The invention relates to new thiadiazolyl or thiazolyl-substituted cephem and cepham compounds, the pharmaceutically acceptable salts and bioprecursors thereof, of antimicrobial activity, processes for preparation thereof, intermediates for preparing the new compounds and to pharmaceutical compositions comprising the new compounds, and methods of using the compositions for treatment of infectious diseases.