684237-55-6Relevant academic research and scientific papers
Scaffold Morphing To Identify Novel DprE1 Inhibitors with Antimycobacterial Activity
Manjunatha,Shandil, Radha,Panda, Manoranjan,Sadler, Claire,Ambady, Anisha,Panduga, Vijender,Kumar, Naveen,Mahadevaswamy, Jyothi,Sreenivasaiah,Narayan, Ashwini,Guptha, Supreeth,Sharma, Sreevalli,Sambandamurthy, Vasan K.,Ramachandran, Vasanthi,Mallya, Meenakshi,Cooper, Christopher,Mdluli, Khisi,Butler, Scott,Tommasi, Ruben,Iyer, Pravin S.,Narayanan, Shridhar,Chatterji, Monalisa,Shirude, Pravin S.
, p. 1480 - 1485 (2019)
We report a novel benzimidazole (BI) based DprE1 inhibitor that resulted from scaffold morphing of a 1,4-azaindole series. The clinical progression of the 1,4-azaindole series from our previous work validates the potential of exploring newer chemical enti
BENZIMIDAZOLES DERIVATIVES AS ANTI-TUBERCULOSIS AGENTS
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, (2020/10/09)
The present invention provides novel compounds of benzimidazole derivatives as anti-tubercular agents and their pharmaceutically acceptable salts for use as bactericidal therapeutics. The invention also provides a pharmaceutical composition comprising a c
