684286-92-8

Upstream product

• 684286-90-6 carbonic acid 9-benzhydryloxy-7-(4-fluorobenzyl)-6,8-dioxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinoxalin-5-yl ester ethyl ester 

Downstream Products

• 684286-93-9 5-benzhydryloxy-7-(4-fluorobenzyl)-8-hydroxy-9-methoxy-7,8-dihydro-pyrrolo[3,4-g]quinoxalin-6-one 
• 684286-94-0 5-benzhydryloxy-7-(4-fluorobenzyl)-8-hydroxy-9-methoxy-1,2,3,4,7,8-hexahydro-pyrrolo[3,4-g]quinoxalin-6-one 
• 684286-95-1 5-benzhydryloxy-7-(4-fluorobenzyl)-8-hydroxy-9-methoxy-1,2,3,4-tetrahydro-pyrrolo[3,4-g]quinoxaline-6,8-dione 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring

This communication details both the syntheses and biological evaluation of a novel class of HIV-1 integrase inhibitors. When the quinoline moiety is replaced with the quinoxoline moiety, the antiviral activity is significantly compromised. Similarly, intr