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684287-32-9

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684287-32-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 684287-32-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,4,2,8 and 7 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 684287-32:
(8*6)+(7*8)+(6*4)+(5*2)+(4*8)+(3*7)+(2*3)+(1*2)=199
199 % 10 = 9
So 684287-32-9 is a valid CAS Registry Number.

684287-32-9Relevant articles and documents

Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors

Jin, Haolun,Cai, Ruby Z.,Schacherer, Laura,Jabri, Salman,Tsiang, Manuel,Fardis, Maria,Chen, Xiaowu,Chen, James M.,Kim, Choung U.

, p. 3989 - 3992 (2007/10/03)

A novel class of tri-cyclic HIV integrase inhibitors were designed based on conformational analysis of 1,6-naphthyridine carboxamide compound L-870810 and docking the designed inhibitor into the active site of our integrase enzyme model. The efficient syn

PRE-ORGANIZED TRICYCLIC INTEGRASE INHIBITOR COMPOUNDS

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Page 319, (2008/06/13)

Tricyclic compounds according to the structure below, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed. Formula (I). Al and A2 are moieties forming a five, six, or seven membered ring. L is a bond or a linker connecting a ring atom of Ar to N. X is O, S, or substituted nitrogen. Ar is aryl or heteroaryl. Q is N, +NR, or CR4. The aryl carbons may be independently substituted with substituents other than hydrogen. The compounds may include prodrug moieties covalently attached at any site.

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