68449-79-6

Usage

Chemical Type

Isothiazole derivative with a phenyl group

Common Uses

Biocide
Preservative
Antimicrobial agent

Applications

Personal care products
Cosmetics
Household products
Industrial applications:
Plastic manufacturing
Rubber manufacturing
Paint manufacturing

Biological Activity

Inhibits growth of:
Bacteria
Fungi
Algae

Safety Considerations

Toxic if ingested
May cause skin irritation
May cause eye irritation

Regulation

Regulated in many countries
Safety precautions required for handling

Upstream product

• 21277-98-5 2-phenylisothiazol-3(2H)-one 
• 1047-89-8 N,N'-Diphenyl-3,3'-dithiobis(propionsaeureamid) 
• 68449-70-7 3-chloro-2-phenyl-isothiazolium; chloride 

Relevant academic research and scientific papers

Isothiazoles. Part 14: New 3-aminosubstituted isothiazole dioxides and their mono- and dihalogeno derivatives

3-Alkylamino- and 3-arylamino isothiazole dioxides unsubstituted at C-4 and C-5 were synthesized starting from dithiopropionic amides. Taking advantage of the direct chlorination during the cyclization process or realizing an addition-elimination process with bromine on the final 3-aminoisothiazole dioxide derivatives, the corresponding 5-chloro-, 4,5-dichloro- or the 4-bromoisothiazole dioxides could also be made available.

Process for preparing 2,3-substituted-1,2,-isothiazolium salt antimicrobials

2,3-Substituted-1,2-isothiazolium salts have antibacterial and antifungal activity and are useful in agriculture against diseases and decay of fruits and vegetables, as well as a slimicide in industry.