68449-80-9

Upstream product

• 2935-88-8 N,N'-dicyclohexyl-3,3'-disulfanediyl-bis-propionamide 
• 68449-71-8 3-chloro-2-cyclohexyl-isothiazolium; chloride 
• 26542-18-7 2-cyclohexyl-isothiazol-3-one 

Downstream Products

• 642088-30-0 N-cyclohexylisothiazol-3-amine 1,1-dioxide 

Relevant academic research and scientific papers

Isothiazoles. Part 14: New 3-aminosubstituted isothiazole dioxides and their mono- and dihalogeno derivatives

3-Alkylamino- and 3-arylamino isothiazole dioxides unsubstituted at C-4 and C-5 were synthesized starting from dithiopropionic amides. Taking advantage of the direct chlorination during the cyclization process or realizing an addition-elimination process with bromine on the final 3-aminoisothiazole dioxide derivatives, the corresponding 5-chloro-, 4,5-dichloro- or the 4-bromoisothiazole dioxides could also be made available.