68464-00-6 Usage
Uses
Used in Pharmaceutical Applications:
(3RS,4SR)-4-hydroxypiperidine-3-carboxylic acid is used as a building block for the synthesis of various pharmaceutical compounds due to its unique structure and functional groups. Its hydrophilic nature and chiral centers may contribute to its potential as a starting material for developing new drugs.
Used in Biological Research:
(3RS,4SR)-4-hydroxypiperidine-3-carboxylic acid is used as a research tool in the study of biological processes and interactions. Its unique structure and functional groups may allow for the investigation of specific biological targets and pathways, potentially leading to the discovery of new therapeutic agents.
Used in Chemical Synthesis:
(3RS,4SR)-4-hydroxypiperidine-3-carboxylic acid is used as an intermediate in the synthesis of more complex organic compounds. Its carboxylic acid functional group can be used for further reactions, such as esterification or amide formation, to create a variety of derivatives with different properties and applications.
Used in Drug Delivery Systems:
(3RS,4SR)-4-hydroxypiperidine-3-carboxylic acid may be used in the development of drug delivery systems, particularly for targeting specific biological receptors or improving the solubility and bioavailability of other drug molecules. Its hydrophilic nature and chiral centers could be exploited to enhance the performance of drug delivery vehicles.
Check Digit Verification of cas no
The CAS Registry Mumber 68464-00-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,4,6 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 68464-00:
(7*6)+(6*8)+(5*4)+(4*6)+(3*4)+(2*0)+(1*0)=146
146 % 10 = 6
So 68464-00-6 is a valid CAS Registry Number.
68464-00-6Relevant academic research and scientific papers
Hydroxy- and amino-substituted piperidinecarboxylic acids as γ-aminobutyric acid agonists and uptake inhibitors
Jacobsen,Labouta,Schaumburg,Falch,Krogsgaard-Larsen
, p. 1157 - 1162 (2007/10/02)
The syntheses of (3RS, 4RS)-4-hydroxypiperidine-3-carboxylic acid (4), (3RS, 5SRJ-5-hydroxypiperiden-3-carboxylic acid (20), (3RS, 4SR)-4-acetamidopiperidine-3-carboxylic acid (10), and (3RS, 5SR)-5-acetamidopiperidine-3-carboxylic acid (18), related to the specific γ-aminobutyric (GABA) uptake inhibitors (RS)-piperidine-3-carboxylic acid (nipecotic acid) and (3RS, 4SR)-4-hydroxypiperidine-3-carboxylic acid (21), are described. Furthermore, (3RS, 4SR)-3-hydroxypiperidine-4-carboxylic acid (14), related to the specific GABA agonist piperidine-4-carboxylic acid (isonipecotic acid), has been synthesized. The structures of 4, 10, 14, 18, and 20 have been established by 270-MHz 1H NMR spectroscopic analyses. The affinity of the compounds for the GABA receptors and for the neuronal (synaptosomal) GABA uptake system in vitro has been measured. Compound 14 interacts selectively with the GABA receptors but less effectively than isonipecotic acid and the cis-isomer 22. Compounds 4, 18, and 20 are inhibitors of the GABA uptake system, although much weaker than nipecotic acid and (3RS, 4SR)-4-hydroxypiperidine-3-carboxylic acid (21). Compound 10 is inactive in both test systems.
