684648-44-0 Usage
Type of compound
Boronic acid derivative
Common use
Reagent for Suzuki-Miyaura coupling reactions in organic synthesis
Physical state
Colorless to light yellow liquid
Odor
Strong
Ability
Forms stable boronate complexes with a wide range of organic compounds
Applications
Pharmaceutical and agrochemical industries for the production of drug and pesticide molecules
Safety concerns
Potential hazardous effects on human health and the environment; requires cautious handling
Check Digit Verification of cas no
The CAS Registry Mumber 684648-44-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,4,6,4 and 8 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 684648-44:
(8*6)+(7*8)+(6*4)+(5*6)+(4*4)+(3*8)+(2*4)+(1*4)=210
210 % 10 = 0
So 684648-44-0 is a valid CAS Registry Number.
684648-44-0Relevant academic research and scientific papers
Ruthenium(0)-catalyzed sp3 C-H bond arylation of benzylic amines using arylboronates
Dastbaravardeh, Navid,Schnuerch, Michael,Mihovilovic, Marko D.
supporting information; experimental part, p. 1930 - 1933 (2012/05/31)
A Ru-catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates is reported. This highly regioselective and efficient transformation can be performed with various combinations of N-(2-pyridyl) substituted benzylamines and arylboronates. Substitution of the pyridine directing group in the 3-position proved to be crucial in order to achieve high arylation yields. Furthermore, the pyridine directing group can be removed in high yields via a two-step protocol.
