68466-20-6Relevant academic research and scientific papers
Synthesis of unsaturated 1,4-heteroatom-containing benzo-fused heterocycles using a sequential isomerization-ring-closing metathesis strategy
Morgans, Garreth L.,Ngidi, E. Lindani,Madeley, Lee G.,Khanye, Setshaba D.,Michael, Joseph P.,de Koning, Charles B.,van Otterlo, Willem A.L.
experimental part, p. 10650 - 10659 (2010/01/16)
A small library of 1,4-benzodioxins and 4H-1,4-benzoxazines was synthesized from the corresponding bis-allyloxy precursors by way of an initial isomerization to the bis-vinyloxy compounds, followed by a ring-closing metathesis using the second generation Grubbs' catalyst (G2). A related strategy, starting from benzene-1,2-dithiol and 2-mercaptophenol, afforded benzodithiin and 1,4-benzoxathiin, respectively.
2,3-DIBROMO-3,4-DIHYDRO-4H-1,4-BENZOXAZINES AND THEIR NUCLEOPHILIC DISPLACEMENT REACTIONS : THE FIRST SYNTHESIS OF 4-ACETYL-4H-1,4-BENZOXAZINE-3-CARBONITRILE
Bartsch, Herbert,Ofner, Maria,Schwarz, Otto,Thomann, Walter
, p. 2789 - 2797 (2007/10/02)
The synthesis of 2,3-dibromo-3,4-dihydro-2H-1,4-benzoxazines is described.Their reaction with alcohols afforded the corresponding 2-bromo-3-alkoxy- and 2,3-dialkoxy derivatives, respectively, which were converted into various 1,4-benzoxazine-3-carbonitril
