68469-60-3

Usage

Uses

Used in Organic Synthesis:
ALLYL(4-METHOXYPHENYL)DIMETHYLSILANE is used as a building block in organic synthesis for its ability to facilitate the creation of complex organic molecules. Its unique structure allows for versatile reactions and the formation of a variety of chemical compounds.
Used in Chemical Research:
In the realm of chemical research, ALLYL(4-METHOXYPHENYL)DIMETHYLSILANE serves as a valuable reagent, enabling scientists to explore new chemical pathways and mechanisms. Its properties contribute to a deeper understanding of organosilicon chemistry and its potential applications.
Used in Pharmaceutical Industry:
ALLYL(4-METHOXYPHENYL)DIMETHYLSILANE is utilized as a reagent in the pharmaceutical industry, where its unique properties can be harnessed to develop new drugs and improve existing ones. Its versatility in chemical reactions makes it a promising candidate for the synthesis of pharmaceutical compounds.
Used in Material Production:
This organosilicon compound is also employed in the production of various materials, capitalizing on its structural and chemical properties to enhance material performance and create innovative products across different industries.

InChI:InChI=1/C12H18OSi/c1-5-10-14(3,4)12-8-6-11(13-2)7-9-12/h5-9H,1,10H2,2-4H3

Upstream product

• 2372-33-0 chlorodimethyl(4-methoxyphenyl)silane 
• 2622-05-1 allylmagnesium bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 4028-23-3 Allylchlorodimethylsilane 
• 623-12-1 4-chloromethoxybenzene 

Downstream Products

• 68469-63-6 3-[p-methoxyphenyl(dimethyl)silyl]-1-propanol 
• 1620144-73-1 C₁₆H₂₃Cl₃O₂S₂Si 
• 1620144-78-6 C₂₂H₂₈Cl₂O₂S₂Si 
• 1373139-22-0 C₁₂H₁₈O₄Si 
• 1373139-29-7 C₂₀H₃₀O₂Si₂ 
• 877-68-9 4-trimethylsilylanisole 
• 1373139-32-2 C₁₅H₂₄O₃Si 
• 54040-89-0 (3-Bromo-propyl)-(4-methoxy-phenyl)-dimethyl-silane 

Relevant academic research and scientific papers

Sodium silylsilanolate enables nickel-catalysed silylation of aryl chlorides

Structurally diverse aryl chlorides were silylated with sodium silylsilanolate reagents in the presence of a Ni(cod)2catalyst complexed with a phosphine ligand; PMe2Ph for electron-rich substrates, and PCy2Ph for electron-deficient ones. The mild reaction conditions allowed the silylation of various aryl chlorides including functionalised drug molecules.

Sequential Synthesis of Organosilicon-Linked 2-Methoxypyridines by Non-Cryogenic ortho-Metallation Using the nBu2TMPMg·Li Reagent and Hydrosilylation

The non-cryogenic synthesis of 5/6- and/or 3-silyl-functionalised 2-methoxypyridines by a 5-Br/Mg exchange process using nBu2iPrMg Li and LiCl and involving C-3 metallation using a novel nBu2TMPMg Li reagent is described. Furthermore, the usefulness of nBu2TMPMg Li in the functionalisation of 2-methoxypyridine at the 3-position with a wide range of electrophiles was successfully tested. The above achievements have allowed the construction of organosilicon-linked 2-methoxypyridines composed of two, three and four rings by the hydrosilylation of 5- and/or 3-SiH(or alkenyl) derivatives using the hitherto rarely applied [Pt(cod)Me2] catalyst. Additionally, the synthesis of a one-chain oligomer consisting of eight 2-methoxypyridines obtained by the hydrosilylation/polymerisation approach, followed by protodesilylation of the SiHMe2 group was also achieved by manipulating the amount of catalyst in the reactions.