68486-03-3

Upstream product

• 855-38-9 P(p-CH₃OC₆H₄)3 
• 72619-19-3 (2-Allyl-4-oxo-azetidin-1-yl)-chloro-acetic acid 3-oxo-1,3-dihydro-isobenzofuran-1-yl ester 
• 72619-18-2 (2-Allyl-4-oxo-azetidin-1-yl)-hydroxy-acetic acid 3-oxo-1,3-dihydro-isobenzofuran-1-yl ester 
• 591-93-5 1,4-Pentadiene 
• 68485-52-9 4-allylazetidin-2-one 

Relevant academic research and scientific papers

Olivanic Acid Analogues. Part 1. Total Synthesis of the 7-Oxo-1-azabicyclohept-2-ene-2-carboxylate System and Some Related β-Lactams

4-Allylazetidin-2-one, prepared from penta-1,4-diene and chlorosulphonyl isocyanate, has been used to synthesise the parent 7-oxo-1-azabicyclohept-2-ene-2-carboxylate system of the naturally occurring olivanic acids, using an intramolecular Wittig reaction to construct the 2,3-double bond.Cyclisation of ketones derived from the 4-allyl grouping produced 3-substituted derivatives, while use of the azetidin-2-one prepared from hexa-1,5-diene and chlorosulphonyl isocyanate has given the homologous 8-oxo-1-azabicyclooct-2-ene system.