685091-51-4

Usage

Imidazole ring

The compound contains a 5-membered imidazole ring, which is an aromatic heterocyclic ring with 2 nitrogen atoms.

Carboxylic acid group

The compound has a carboxylic acid group (-COOH) attached to the imidazole ring, which is known for its acidic properties.

Bromophenylmethyl group

The compound has a bromine atom attached to a phenyl ring, which is connected to the imidazole ring through a methylene group (-CH2-).

Hydroxyisopropyl group

The compound has a hydroxyl group (-OH) attached to a isopropyl group (1-methylethyl), which is connected to the imidazole ring.

Propyl group

The compound has a propyl group (3-carbon alkyl chain) attached to the hydroxyisopropyl group.

Ethyl ester

The compound is an ethyl ester, meaning it has an ethoxy group (-OCH2CH3) attached to the carboxylic acid group.

Pharmaceutical use

Due to its unique structure and potential biological activity, the compound may be used as a pharmaceutical ingredient or in organic synthesis.

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 144689-93-0 ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylate 

Downstream Products

• 1014987-69-9 5-(1-hydroxy-1-methyl-ethyl)-3-{2'-[2-(1-methyl-1-phenyl-ethyl)-2H-tetrazol-5-yl]-biphenyl-4-yl-methyl}-2-propyl-3H-imidazol-4-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Convergent Synthesis of Angiotensin II Receptor Blockers through C-H Arylation of 1-Benzyl-5-phenyl-1 H -tetrazole with Functionalized Aryl Bromides

Highly convergent synthesis of angiotensin II receptor blockers has been accomplished by means of late-stage C-H arylation using functionalized aryl bromides. C-H arylation of 1-benzyl-5-phenyl-1 H -tetrazole with aryl bromides carrying methyl 2-ethoxyben

METHOD FOR PRODUCING N-PROTECTED SARTAN DERIVATIVE

PROBLEM TO BE SOLVED: To provide a method for efficiently producing intermediates of candesartan cilexetil and olmesartan. SOLUTION: The present invention provides a method for producing an N-protected sartan by causing an N-(4-bromobenzyl) imidazole deri

A PROCESS FOR THE PREPARATION OF PHENYLTETRAZOLE COMPOUNDS

A process for the preparation of olmesartan medoxomil, and derivatives thereof, by use of novel phenyltetrazole intermediates.

A process for the preparation of phenyltetrazole compounds

A process for the preparation of olmesartan medoxomil, and derivatives thereof, by use of novel phenyltetrazole intermediates.