6853-99-2 Usage
Uses
Used in Pharmaceutical Industry:
(22S)-22,25-Epoxy-3β,17,20-trihydroxylanosta-7,9(11)-dien-18-oic acid γ-lactone serves as a lead compound for the development of new drugs due to its demonstrated antimicrobial, anti-inflammatory, and anti-tumor capabilities. Its multifaceted biological activities make it a valuable asset in the creation of treatments for a range of diseases and conditions.
Used in Antimicrobial Applications:
In the field of infectious diseases, (22S)-22,25-Epoxy-3β,17,20-trihydroxylanosta-7,9(11)-dien-18-oic acid γ-lactone is utilized as an antimicrobial agent to combat various pathogens. Its ability to inhibit microbial growth suggests potential use in treating bacterial and fungal infections.
Used in Anti-inflammatory Applications:
(22S)-22,25-Epoxy-3β,17,20-trihydroxylanosta-7,9(11)-dien-18-oic acid γ-lactone is applied as an anti-inflammatory agent, targeting the reduction of inflammation in conditions such as arthritis, dermatitis, and other inflammatory disorders. Its capacity to modulate inflammatory responses could lead to effective treatments with fewer side effects compared to current options.
Used in Anti-tumor Applications:
Cancer research and treatment can benefit from (22S)-22,25-Epoxy-3β,17,20-trihydroxylanosta-7,9(11)-dien-18-oic acid γ-lactone as an anti-tumor agent. Its potential to impede tumor growth and proliferation makes it a candidate for further exploration in oncology, possibly leading to novel cancer therapies.
Used in Drug Development:
The unique structure and properties of (22S)-22,25-Epoxy-3β,17,20-trihydroxylanosta-7,9(11)-dien-18-oic acid γ-lactone make it an intriguing subject for medicinal chemistry research. Its exploration could lead to the discovery of new drug candidates with improved efficacy and selectivity for various therapeutic targets.
Check Digit Verification of cas no
The CAS Registry Mumber 6853-99-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,5 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6853-99:
(6*6)+(5*8)+(4*5)+(3*3)+(2*9)+(1*9)=132
132 % 10 = 2
So 6853-99-2 is a valid CAS Registry Number.
6853-99-2Relevant academic research and scientific papers
Invertebres marins du lagon neocaledonien IV. Saponines et sapogenines d'une holothurie, Actinopyga flammea
Bhatnagar, Subodh,Dudouet, Brigitte,Ahond, Alain,Poupat, Christiane,Thoison, Odile,et al.
, p. 124 - 129 (2007/10/02)
Nine triterpenoid saponins have been isolated from the New Caledonian sea-cucumber, Actinopyga flammea.Holothurin A and B, echinoside A, 24-dehyroechinoside A and 22-hydroxy ξ-echinoside A (holothurin A1) are known compounds, whereas, 24(S)-hydroxy-25-dehydro-echinoside A, 22 ξ-hydroxy-24-dehydro-echinoside A, 22 ξ-acetoxy-echinoside A and 25-hydroxy-dehydroechinoside A are new compounds.Acid hydrolysis of the crude saponins yielded six sapogenins which have been identified as: 22,25-oxydo-holothurinogenin, holothurinogenin, 24-dehydro-holothurinogenin, griseogenin, koellikerigenin and the previously unreported 16-keto-holothurinogenin.
GLYCOSIDES OF MARINE INVERTEBRATES. XXVI. HOLOTHURIN A FROM THE PACIFIC OCEAN HOLOTHURIAN Holothuria squamifera. ISOLATION OF THE NATIVE AGLYCONE
Ivanova, N. S.,Smetanina, O. F.,Kuznetsova, T. A.
, p. 424 - 426 (2007/10/02)
The known triterpene tetraoside holothurin A has been isolated from the Pacific Ocean holothurian Holothuria squamifera.By using two independent methods - enzymatic cleavage and two-stage Smith degradation - 22,25-epoxyholost-9(11)-ene-3β,12α,17α-triol, C30H46O6, which is the native aglycone of holothurin A, was obtained.The structure of the native aglycone has been established on the basis of the results of IR, mass, and PMR spectroscopy.
