68535-59-1Relevant academic research and scientific papers
COMPOUNDS USEFUL AS INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE
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, (2019/04/11)
The present invention relates to compounds of general Formula (I), and/or tautomers, enantiomers, solvates, hydrates, and pharmaceutically acceptable salts thereof. The present invention also relates to compounds of Formula (I) for use in therapy, methods
New potent C2-symmetric malaria plasmepsin I and II inhibitors.
Oscarsson, Karin,Oscarson, Stefan,Vrang, Lotta,Hamelink, Elizabeth,Hallberg, Anders,Samuelsson, Bertil
, p. 1235 - 1246 (2007/10/03)
A series of malaria plasmepsin (Plm) I and II inhibitors containing a C(2)-symmetric core structure have been synthesised and tested for protease inhibition activity. These compounds can be prepared using a straightforward synthesis involving a phenol nuc
