685513-95-5 Usage
Uses
Used in Pharmaceutical Industry:
4,5-Dichloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine is used as a building block for the production of pharmaceuticals, given its ability to contribute to the development of complex organic molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4,5-Dichloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine is utilized as a component in the synthesis of agrochemicals, where its reactivity and structural features are harnessed to create compounds with pesticidal or herbicidal properties.
Used in Materials Science:
4,5-Dichloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine is employed in materials science as a precursor for the synthesis of novel materials with specific properties, such as those with potential applications in electronics or advanced composites.
Used in Chemical Research and Development:
As a versatile reagent, 4,5-Dichloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine is used in chemical research and development for studying the properties of complex organic molecules and for the development of new synthetic methodologies. Its protective triisopropylsilyl group is particularly valuable in these processes, allowing for the selective protection and deprotection of reactive sites during molecule assembly.
Check Digit Verification of cas no
The CAS Registry Mumber 685513-95-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,5,5,1 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 685513-95:
(8*6)+(7*8)+(6*5)+(5*5)+(4*1)+(3*3)+(2*9)+(1*5)=195
195 % 10 = 5
So 685513-95-5 is a valid CAS Registry Number.
685513-95-5Relevant academic research and scientific papers
A 5 - chloro - 1 H - pyrrolo [2, 3 - B] pyridine - 4 - amine synthesis method (by machine translation)
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, (2017/11/16)
The invention relates to a 5 - chloro - 1 H - pyrrolo [2, 3 - B] pyridine - 4 - amine synthesis method. Mainly solves the method lacks the quantity compound into the technical problem. The invention synthetic method comprises the following steps: 4 - chloro - 7 - azaindole in and sodium hydride in tetrahydrofuran, three different propyl silane to react at room temperature, to produce compound 1; compound 1 in zhongzhong butyl lithium in tetrahydrofuran and, hexachloroethane low-temperature reaction, generating compound 2; compound 2 and [...] sodium, ammonium chloride, in N, N - dimethyl formamide in the reaction under the high temperature, generating compounds 3; under the catalytic action of palladium, compound 3 in ethanol was hydrogenated under the atmospheric pressure, to produce the target compound 4. As expensive fine chemical products, 5 - chloro - 1 H - pyrrolo [2, 3 - B] pyridine - 4 - amine in widely applied in the pharmaceutical industry. (by machine translation)
Synthesis of functionalized 7-azaindoles via directed ortho-metalations
L'Heureux, Alexandre,Thibault, Carl,Ruel, Réjean
, p. 2317 - 2319 (2007/10/03)
Functionalization at C-5 of 4-fluoro- and 4-chloro-1-triisopropylsilyl-7- azaindole, 1 and 2, respectively, leads to a variety of new substituted 7-azaindole derivatives. We also describe two approaches to introduce functionality at C-6.
