685513-96-6

Basic information

• Product Name: (5-broMo-4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane
• Synonyms: (5-broMo-4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane;5-bromo-4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine;5-Bromo-4-chloro-1-(triisopropylsilanyl)-7-azaindole
• CAS NO: 685513-96-6
• Molecular Formula: C₁₆H₂₄BrClN₂Si
• Molecular Weight: 387.81766
• EINECS: -0
• Mol File: 685513-96-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (5-broMo-4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane(CAS DataBase Reference)
• NIST Chemistry Reference: (5-broMo-4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane(685513-96-6)
• EPA Substance Registry System: (5-broMo-4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane(685513-96-6)

Safety Data

• Hazardous Substances Data: 685513-96-6(Hazardous Substances Data)

Usage

General Description

(5-broMo-4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane is a chemical compound with the molecular formula C15H20BrClN2Si. It is a silane compound containing both bromo and chloro substituents on a pyrrolopyridine ring. The presence of the tri(propan-2-yl) group indicates that there are three isopropyl groups bonded to the silicon atom. (5-broMo-4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane's specific properties and uses may vary, but silanes are commonly used as coupling agents in composite materials, adhesives, and coatings. The bromo and chloro groups may also make this compound useful in organic synthesis and pharmaceutical research as a reactive intermediate. Additionally, its unique structure and potential reactivity make it a valuable tool for exploring the chemistry of pyrrolopyridine derivatives.

Upstream product

• 55052-24-9 1H-Pyrrolo[2,3-b]pyridine-7-oxide 
• 271-63-6 7-Azaindole 
• 558-13-4 carbon tetrabromide 
• 651744-48-8 4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine 
• 55052-28-3 4-chloro-7-azaindole 
• 13154-24-0 triisopropylsilyl chloride 

Downstream Products

• 1596337-81-3 5-bromo-4-chloro-1-[(4-methylphenyl)sulfonyl-1H-pyrrolo[2,3-b]pyridine] 

Relevant articles and documents

TAM KINASE INHIBITORS

Described herein are compounds, methods of making such compounds, compositions (e.g., pharmaceutical compositions/medicaments) that include such compounds, and methods of using such compounds to treat diseases, such as cancer.

PYRROLOPYRIDINES AS KINASE INHIBITORS

Compounds of Formula (I) are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.Formula, (I).