685517-71-9

Usage

Uses

Used in Pharmaceutical Industry:
PYRIDINE, 2,6-DIFLUORO-4-IODOis used as a building block for the synthesis of various pharmaceuticals. Its unique structure and halogenated nature allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
PYRIDINE, 2,6-DIFLUORO-4-IODOis utilized as a key intermediate in the production of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness and selectivity in controlling pests and weeds.
Used in Organic Synthesis:
PYRIDINE, 2,6-DIFLUORO-4-IODOserves as a valuable reagent in organic synthesis, enabling the creation of a wide range of organic compounds. Its presence facilitates various chemical reactions, contributing to the synthesis of complex organic molecules.
Used in Chemical Production:
PYRIDINE, 2,6-DIFLUORO-4-IODOis employed as an intermediate in the manufacturing process of other chemicals. Its versatility and reactivity make it an essential component in the production of various chemical compounds, further expanding its applications across different industries.

Upstream product

• 685517-67-3 2,6-difluoro-3-iodopyridine 
• 1513-65-1 2,6-difluoro pyridine 

Downstream Products

• 401816-16-8 (2,6-difluoropyridin-4-yl)boronic acid 
• 1421430-96-7 trans-4-(6-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-ylamino)cyclohexanol 
• 1421430-93-4 N-cyclohexyl-6-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine 
• 1341213-35-1 3-(2,6-difluoropyridin-4-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

Steering On-Surface Reactions by a Self-Assembly Approach

4,4′-Bis(2,6-difluoropyridin-4-yl)-1,1′:4′,1′′-terphenyl (BDFPTP) molecules underwent dehydrocyclization and covalent coupling reactions on Au(111) according to scanning tunneling microscopy (STM) measurements and density functional theory (DFT) calculati

Pinning-down molecules in their self-assemblies with multiple weak hydrogen bonds of C[sbnd]H?F and C[sbnd]H?N

Two-dimensional self-assemblies of four partially fluorinated molecules, 1,4-bis(2,6-difluoropyridin-4-yl)benzene, 4,4′-bis(2,6-difluoropyridin-4-yl)-1,1′-biphenyl, 4,4′-bis(2,6-difluoropyridin-4-yl)-1,1′:4′,1″-terphenyl and 4,4′-bis(2,6-difluoropyridin-3-yl)-1,1′-biphenyl, involving weak intermolecular C[sbnd]H?F and C[sbnd]H?N hydrogen bonds were systematically investigated on Au(111) with low-temperature scanning tunneling microscopy. The inter-molecular connecting modes and binding sites were closely related to the backbones of the building blocks, i.e., the molecule length determines its binding sites with neighboring molecules in the assemblies while the attaching positions of the N and F atoms dictate its approaching and docking angles. The experimental results demonstrate that multiple weak hydrogen bonds such as C[sbnd]H?F and C[sbnd]H?N can be efficiently applied to tune the molecular orientations and the self-assembly structures accordingly.

Synthetic entries to substituted bicyclic pyridones

(Chemical Equation Presented) The synthesis of 6,6- and 5,6-bicyclic pyridone scaffolds has been completed using (i) an intramolecular Mitsunobu reaction and/or (ii) hydrolysis of a bicyclic pyridinium salt intermediate. Regioselective functionalization o

The structural proliferation of 2,6-difluoropyridine through organometallic intermediates

Contrary to a literature claim, 2,6-difluoropyridine-3-carboxaldehyde can be readily prepared by consecutive treatment of 2,6-difluoropyridine with lithium diisopropylamide and N,N-dimethylformamide. Regioselective displacements of fluorine from the aldehyde by nucleophiles were carried out. To demonstrate the versatility of the organometallic approach, some two dozens of further 2,6-difluoropyridine derivatives were prepared applying a combination of modern organometallic methods such as site selective hydrogen/metal and halogen/metal permutations and deprotonation-triggered heavy halogen migrations. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.