68556-50-3Relevant articles and documents
A convenient method for the preparation of functionalized N-acylsulfenamides from primary amides
Musiejuk, Mateusz,Witt, Dariusz
, p. 305 - 310 (2016)
We have developed a convenient method for the synthesis of functionalized N-acylsulfenamides under mild conditions and in moderate to good yields. The designed method is based on the reaction of (5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)-disulfanyl derivatives with nitrogen nucleophiles generated from primary amides or imides and sodium hydride. The developed method allows for the preparation of N-acylsulfenamides bearing additional hydroxyl, carboxyl, or amino functionalities.