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685563-24-0

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685563-24-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 685563-24-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,5,5,6 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 685563-24:
(8*6)+(7*8)+(6*5)+(5*5)+(4*6)+(3*3)+(2*2)+(1*4)=200
200 % 10 = 0
So 685563-24-0 is a valid CAS Registry Number.

685563-24-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name prop-2-ynyl 1H-pyrrole-2-carboxylate

1.2 Other means of identification

Product number -
Other names propargyl 1H-pyrrole-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:685563-24-0 SDS

685563-24-0Downstream Products

685563-24-0Relevant articles and documents

Anti-HIV-1 activity of pyrryl aryl sulfone (PAS) derivatives: Synthesis and SAR studies of novel esters and amides at the position 2 of the pyrrole nucleus

Silvestri, Romano,Artico, Marino,La Regina, Giuseppe,De Martino, Gabriella,La Colla, Massimiliano,Loddo, Roberta,La Colla, Paolo

, p. 201 - 210 (2007/10/03)

A SAR study has been performed in order to evaluate how much the ester function could be a determinant for the anti-human immunodeficiency virus type-1 activity of pyrryl aryl sulfones (PASs), a potent family of non-nucleoside reverse transcriptase (RT) inhibitors discovered in the last years. Twenty-three new esters were prepared with the aim to enhance the inhibitory potency of 4a and 4c, two PAS agents endowed with good activity (EC50 = 0.14 μM) and deprived of cytotoxicity up to >200 μM. None of test derivatives was as potent as 4a and 4c and lacked of selectivity due to their higher cytotoxicity (compounds 22-25). Antiviral activity correlate with an ester ramified chain.

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