685835-73-8

Basic information

• Product Name: 2-Propanesulfonic acid, (2R)-2-hydroxy-2-phenylethyl ester
• CAS NO: 685835-73-8
• Molecular Formula: C11H16O4S
• Molecular Weight: 244.312
• Mol File: 685835-73-8.mol

Chemical Properties

• CAS DataBase Reference: 2-Propanesulfonic acid, (2R)-2-hydroxy-2-phenylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanesulfonic acid, (2R)-2-hydroxy-2-phenylethyl ester(685835-73-8)
• EPA Substance Registry System: 2-Propanesulfonic acid, (2R)-2-hydroxy-2-phenylethyl ester(685835-73-8)

Safety Data

• Hazardous Substances Data: 685835-73-8(Hazardous Substances Data)

Upstream product

• 10147-37-2 Isopropylsulfonyl chloride 
• 16355-00-3 (R)-1-phenyl-1,2-ethanediol 

Downstream Products

• 685835-76-1 (1R)-2-O-isopropanesulfonyl-1-phenyl-1-O-vinyl-1,2-ethanediol 
• 685835-82-9 (1R,4'S)-1-O-(azetidin-2'-on-4'-yl)-2-O-(1'',1''-dimethyl-2''-phenyl-ethanesulfonyl)-1-phenyl-1,2-ethanediol 
• 685835-83-0 (1R,4'R)-1-O-(azetidin-2'-on-4'-yl)-2-O-(1'',1''-dimethyl-2''-phenyl-ethanesulfonyl)-1-phenyl-1,2-ethanediol 
• 685835-77-2 (1R)-2-O-(1',1'-dimethyl-2'-phenyl-ethanesulfonyl)-1-phenyl-1-O-vinyl-1,2-ethanediol 
• 685835-81-8 (1R,4'S)-1-O-(azetidin-2'-on-4'-yl)-2-O-isopropane-sulfonyl-1-phenyl-1,2-ethanediol 
• 685835-80-7 (1R,4'R)-1-O-(azetidin-2'-on-4'-yl)-2-O-isopropane-sulfonyl-1-phenyl-1,2-ethanediol 

Relevant articles and documents

Synthesis, biological, and chiroptical activity of 3-phenyl-clavams

The [2+2]cycloaddition of chlorosulfonyl isocyanate to simple vinyl ethers derived from the 2-O-sulfonylated (R) and (S) 1-phenyl-1,2-ethanediol leads to 4-alkoxy-azetidin-2-ones with a moderate stereoselectivity. The cycloaddition to analogous (Z)-propenyl ethers proceeds stereospecifically with the retention of the olefin configuration. The intramolecular alkylation of β-lactam nitrogen atom furnished all possible stereoisomers of 3-phenyl- and 6-methyl-3-phenyl-clavams. The biological and chiroptical activity of synthesized clavams was investigated. The (3R,5R)-diastereomer 30 showed higher inhibition of bacterial enzymes than other related compounds.