685847-72-7Relevant academic research and scientific papers
Radical Carbonylation under Low CO Pressure: Synthesis of Esters from Activated Alkylamines at Transition Metal-Free Conditions
Zhao, Fengqian,Ai, Han-Jun,Wu, Xiao-Feng
, p. 927 - 932 (2021)
High CO pressure (> 40 bar) is usually needed in radical carbonylation reactions in the absence of metal catalyst. In this communication, we developed a transition-metal-free radical carbonylation of activated alkylamines with phenols and alcohols under low CO pressure (1—6 bar). Various esters were obtained in moderate to excellent yields under simple reaction conditions with good functional group compatibility.
