685885-53-4

Upstream product

• 1730-25-2 allylmagnesium bromide 
• 685885-52-3 (3R,5S,6R)-3-Benzyloxy-5-methoxy-6-methoxymethyl-tetrahydro-pyran-2-one 
• 685885-51-2 (2S,3R,5S,6R)-3-Benzyloxy-2,5-dimethoxy-6-methoxymethyl-tetrahydro-pyran 

Downstream Products

• 685885-59-0 Benzoic acid (2R,3S,4aR,7aS,9R,10S,11aR,12aS)-3-((R)-2-cyano-1-hydroxy-ethyl)-10-methoxy-9-methoxymethyl-3-methyl-6-oxo-dodecahydro-4,8,12-trioxa-dibenzo[a,d]cycloocten-2-yl ester 
• 685885-60-3 Benzoic acid (2R,3R,4aR,7aS,9R,10S,11aR,12aS)-3-((R)-2-cyano-1-triisopropylsilanyloxy-ethyl)-10-methoxy-9-methoxymethyl-3-methyl-6-oxo-dodecahydro-4,8,12-trioxa-dibenzo[a,d]cycloocten-2-yl ester 
• 1053713-90-8 1-((2S,3R,5S,6R)-3-Benzyloxy-5-methoxy-6-methoxymethyl-tetrahydro-pyran-2-yl)-propan-2-one 

Relevant academic research and scientific papers

Stereoselective synthesis of the fully functionalized HIJ-ring framework of ciguatoxin

An efficient convergent synthetic route to construct the HIJ-ring system of ciguatoxin was achieved via stereo controlled eight-membered ring formation by using acetylene cobalt complex and subsequent six-membered ring formation through intramolecular 1,4-addition reaction.