686268-88-2

Upstream product

• 931402-02-7 ethyl 4-hydroxy-2-oxo-1-{[(1E)-phenylmethylidene]amino}-1,2-dihydro-3-quinolinecarboxylate 
• 33906-30-8 2-hydrazinobenzoic acid hydrochloride 
• 4036-59-3 2-[(2E)-2-benzylidenehydrazino]benzoic acid 
• 108-94-1 cyclohexanone 
• 686267-68-5 1-amino-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone 

Downstream Products

• 686262-92-0 1-butyl-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1,8-naphthyridin-2(1H)-one 

Relevant academic research and scientific papers

Inhibitors of HCV NS5B polymerase: Synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines

N-1-Alkylamino and N-1-alkyloxy-4-hydroxyquinolon-3-yl benzothiadiazines were synthesized and evaluated as inhibitors of genotype 1 HCV polymerase. The N-1-alkyloxy derivatives were not potent inhibitors, however N-1-alkylamino derivatives displayed compa

Anti-infective agents

Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.