68638-99-3Relevant academic research and scientific papers
Synthesis and cytotoxic activity of new azepino[3′,4′:4,5]pyrrolo[2,1-a]isoquinolin-12-ones
Martinez, Roberto,Arzate, Martha Menes,Ramirez-Apan, Ma. Teresa
experimental part, p. 1849 - 1856 (2009/05/26)
A series of azepino[3′,4′:4,5]pyrrolo[2,1-a]isoquinolin-12-ones (3a-f), that were conformationally restricted analogs of lead compound 2, were designed as potential cytotoxic compounds and synthesized using a radical oxidative aromatic substitution reacti
Efficient, "tin-free" radical cyclization to aromatic systems. Synthesis of 5,6,8,9,10,11-hexahydroindolo[2,1-a]isoquinolines
Menes-Arzate, Martha,Martínez, Roberto,Cruz-Almanza, Raymundo,Muchowski, Joseph M.,Osornio, Yazmin M.,Miranda, Luis D.
, p. 4001 - 4004 (2007/10/03)
Efficient radical cyclization of alkyl iodides to various aromatic systems including pyrrole, indole, isoquinolone, pyridone, and benzene, mediated by dicumyl peroxide, is described. The methodology was used to provide access to 5,6,8,9,10,11-hexahydroindolo[2,1-a]isoquinoline derivatives.
