68641-02-1

Basic information

• Product Name: 1-propanoyl-1,3-dihydro-2H-indol-2-one
• CAS NO: 68641-02-1
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.2105
• Mol File: 68641-02-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 404.3°C at 760 mmHg
• Flash Point: 200.8°C
• Density: 1.229g/cm³
• Vapor Pressure: 9.51E-07mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 1-propanoyl-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-propanoyl-1,3-dihydro-2H-indol-2-one(68641-02-1)
• EPA Substance Registry System: 1-propanoyl-1,3-dihydro-2H-indol-2-one(68641-02-1)

Safety Data

• Hazardous Substances Data: 68641-02-1(Hazardous Substances Data)

Usage

Physical Appearance

Yellow to brown crystalline solid
The color and form of the compound in its pure state.

Odor

Musky
The distinct smell that the compound emits.

Usage in Pharmaceutical Production

Commonly used
The compound's widespread application in the creation of various pharmaceuticals.

Synthesis of Indole-based Drugs

Particularly used
Its role in producing drugs that are based on the indole structure.

Application in Organic Chemistry

Building block for complex molecules
The compound's function as a starting material for synthesizing other complex organic molecules.

Pharmacological Properties

Potential anti-inflammatory and analgesic agent
The possible therapeutic effects of the compound, which require further research for confirmation.

Further Research Needs

Medicinal applications not fully understood
The necessity for additional studies to fully explore and understand the compound's potential uses in medicine.

Upstream product

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Relevant articles and documents

Synthesis of oxindole from acetanilide via Ir(iii)-catalyzed C-H carbenoid functionalization

Herein we disclose the first report on the synthesis of oxindole derivatives from acetanilide via Ir(iii)-catalyzed intermolecular C-H functionalization with diazotized Meldrum's acid. A broad range of substituted anilides were found to react smoothly under the Ir(iii)-catalytic system to afford the corresponding N-protected oxindoles. The N-protecting groups, such as Ac, Bz or Piv, can be easily removed to furnish the oxindole. Various synthetic applications of the synthesized oxindole were also demonstrated.