68655-66-3Relevant academic research and scientific papers
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR)
Ciccone, Lidia,Nencetti, Susanna,Rossello, Armando,Stura, Enrico Adriano,Orlandini, Elisabetta
, p. 40 - 51 (2016/12/03)
Transthyretin (TTR), a β-sheet-rich tetrameric protein, in equilibrium with an unstable amyloidogenic monomeric form is responsible for extracellular deposition of amyloid fibrils, is associated with the onset of neurodegenerative diseases, such as senile
