68692-77-3

Usage

Uses

Used in Industrial and Laboratory Settings:
(1-phenylcyclohexane)methanol is used as a solvent for various chemical processes and reactions due to its ability to dissolve a broad range of substances.
Used in Pharmaceutical Synthesis:
(1-phenylcyclohexane)methanol is used as a precursor in the synthesis of various pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Fragrance and Flavor Production:
(1-phenylcyclohexane)methanol is used as a key component in the production of fragrances and flavors, capitalizing on its aromatic properties to create desirable scents and tastes.
Used in Organic Chemistry Research:
(1-phenylcyclohexane)methanol is used as a valuable building block in organic chemistry research, enabling the exploration of new chemical reactions and the creation of novel compounds.
It is important to handle (1-phenylcyclohexane)methanol with care, as it can be toxic and may cause irritation if it comes into contact with the skin or eyes.

InChI:InChI=1/C13H18O/c14-11-13(9-5-2-6-10-13)12-7-3-1-4-8-12/h1,3-4,7-8,14H,2,5-6,9-11H2

Upstream product

• 1135-67-7 1-phenyl-cyclohexanecarboxylic acid 
• 17380-78-8 methyl 1-phenyl-1-cyclohexanecarboxylate 
• 2201-23-2 1-phenyl-1-cyclohexanecarbonitrile 
• 111-24-0 1,5-dibromo-pentane 
• 22612-69-7 1-phenylcyclohexane-1-carbaldehyde 
• 140-29-4 phenylacetonitrile 

Downstream Products

• 1135-67-7 1-phenyl-cyclohexanecarboxylic acid 
• 32294-72-7 (1-phenylcyclohexyl)acetonitrile 
• 500340-80-7 methanesulfonic acid 1-phenylcyclohexylmethyl ester 
• 22612-69-7 1-phenylcyclohexane-1-carbaldehyde 
• 1616924-40-3 5-benzyloxy-6-hydroxy-2-(1-phenylcyclohexylmethyl)pyrimidine-4-carboxylic acid [2-(tert-butyldimethylsilanyloxy)ethyl]isopropylamide 
• 1616924-39-0 5-benzyloxy-6-hydroxy-2-(1-phenylcyclohexylmethyl)pyrimidine-4-carboxylic acid 
• 1616924-38-9 5-benzyloxy-6-hydroxy-2-(1-phenylcyclohexylmethyl)pyrimidine-4-carboxylic acid tert-butyl ester 
• 1616924-37-8 2-(1-phenylcyclohexyl)acetamidine hydrochloride 
• 1616922-11-2 9-hydroxy-2-isopropyl-6-(1-phenylcyclohexylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione 
• 17380-78-8 methyl 1-phenyl-1-cyclohexanecarboxylate 
• 136089-16-2 O-<2-<2-(diethylamino)ethoxy>ethyl>-1-phenyl-1-cyclohexanemethanol 
• 1616924-42-5 9-benzyloxy-2-isopropyl-6-(1-phenylcyclohexylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione 
• 1616924-41-4 5-benzyloxy-6-hydroxy-2-(1-phenylcyclohexylmethyl)pyrimidine-4-carboxylic acid (2-hydroxyethyl)isopropylamide 

Relevant academic research and scientific papers

Selective Aerobic Oxidation of Primary Alcohols to Aldehydes

The 2-azaadamantane- N -oxyl (AZADO)- and 9-azanoradamantane- N -oxyl (nor-AZADO)-catalyzed selective oxidation of primary alcohols to the corresponding aldehydes is described. The use of tert -butyl nitrite as the co-catalyst enables efficient aerobic oxidation in MeCN instead of previously reported AcOH; this is important for the selectivity of the reaction. The addition of a solution of saturated aqueous NaHCO 3 after the completion of the reaction was effective to suppress the overoxidation of the product to the corresponding carboxylic acid during the workup.

Br?nsted Acid-Catalyzed Intramolecular Hydroarylation of β-Benzylstyrenes

Using triphenylmethylium tetrakis(pentafluorophenyl)borate as a convenient Br?nsted acid precatalyst, β-(α,α-dimethylbenzyl)styrenes are shown to cyclize efficiently to afford a variety of new indanes that possess a benzylic quaternary center. The geminal dimethyl-containing quaternary center is proposed to be necessary to arm the substrate for cyclization through steric biasing.

PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE

The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.

APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

Disclosed are compounds which inhibit the activity of anti-apoptotic Bc1-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bc1-xL protein.

Novel 1-phenylcycloalkanecarboxylic acid derivatives as potential anticonvulsant agents

A series of analogues based on the anticonvulsant carbetapentane (1, 2-[2- (diethylamino)ethoxy]ethyl 1-phenyl-1-cyclopentylcarboxylate) was prepared as potential novel anticonvulsant drugs. Structure-activity relationships of analogues in which the ester function and cyclopentane moieties were modified have been investigated by evaluating their ability to prevent seizures in the rat maximal electroshock test. These compounds (11, ED50 = 16 μmol/kg; 12, ED50 = 86 μmol/kg, and 23, ED50 = 173 μmol/kg) were effective anticonvulsants. Compound 11, an alkyl ether derivative of 1, was more potent than the parent compound (ED50 = 48 μmol/kg) and also showed a 2-fold increase in potency compared to that of the prototypic anticonvulsant drug diphenylhydantoin.