68695-62-5 Usage
Description
N-(Phenylmethyl)carbamimidothioic acid methyl ester is a chemical compound with the molecular formula C9H12N2OS. It is an ester derivative of carbamimidothioic acid, characterized by the unique structure of a phenylmethyl group attached to the nitrogen atom. This white solid has a melting point of approximately 64-66°C and a molecular weight of 196.27 g/mol.
Uses
Used in Pharmaceutical Industry:
N-(Phenylmethyl)carbamimidothioic acid methyl ester is used as a reagent in chemical synthesis for the development of new pharmaceutical compounds. Its unique structure allows for the creation of novel molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical field, N-(Phenylmethyl)carbamimidothioic acid methyl ester is utilized as a building block for the preparation of various agrochemical compounds. Its properties can contribute to the development of innovative products for crop protection and enhancement.
It is crucial to handle N-(Phenylmethyl)carbamimidothioic acid methyl ester with care and adhere to safety guidelines when working with this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 68695-62-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,6,9 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 68695-62:
(7*6)+(6*8)+(5*6)+(4*9)+(3*5)+(2*6)+(1*2)=185
185 % 10 = 5
So 68695-62-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2S/c1-12-9(10)11-7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H2,10,11)
68695-62-5Relevant articles and documents
Aminoguanidine hydrazone derivatives as non-peptide NPFF1 receptor antagonists reverse opioid induced hyperalgesia
Hammoud, Hassan,Elhabazi, Khadija,Quillet, Rapha?lle,Bertin, Isabelle,Utard, Valérie,Laboureyras, Emilie,Bourguignon, Jean-Jacques,Bihel, Frederic,Simonnet, Guy,Simonin, Frederic,Schmitt, Martine
, (2018/05/15)
Neuropeptide FF receptors (NPFF1R and NPFF2R) and their endogenous ligand Neuropeptide FF have been shown previously to display anti-opioid properties and to play a critical role in the adverse effects associated with chronic administrations of opiates including the development of opioid-induced hyperalgesia and analgesic tolerance. In this work, we sought to identify novel NPFF receptors ligands by focusing our interest on a series of heterocycles as rigidified non-peptide NPFF receptor ligands, starting from already described aminoguanidine hydrazones (AGH's). Binding experiments and functional assays highlighted AGH 1n and its rigidified analog 2-amino-dihydropyrimidine 22e for in vivo experiments. As earlier shown with the prototypical dipeptide antagonist RF9, both 1n and 22e reduced significantly the long lasting fentanyl-induced hyperalgesia in rodents. Altogether these data indicate that AGH rigidification maintains nanomolar affinities for both NPFF receptors, while improving antagonist character towards NPFF1R.