687631-27-2Relevant academic research and scientific papers
Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents
Seefeld, Mark A,Miller, William H,Newlander, Kenneth A,Burgess, Walter J,Payne, David J,Rittenhouse, Stephen F,Moore, Terrance D,DeWolf Jr., Walter E,Keller, Paul M,Qiu, Xiayang,Janson, Cheryl A,Vaidya, Kalindi,Fosberry, Andrew P,Smyth, Martin G,Jaworski, Deborah D,Slater-Radosti, Courtney,Huffman, William F
, p. 2241 - 2244 (2007/10/03)
An SAR study of a screening lead has led to the identification of 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as inhibitors of Staphylococcus aureus enoyl acyl carrier protein reductase (FabI).
