68776-47-6

Basic information

• Product Name: 1beta-Hydroxyalantolactone
• Synonyms: 1beta-Hydroxyalantolactone;(3aR,5S,8R,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-8-hydroxy-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one
• CAS NO: 68776-47-6
• Molecular Formula: C₁₅H₂₀O₃
• Molecular Weight: 248.3175
• Mol File: 68776-47-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1beta-Hydroxyalantolactone(CAS DataBase Reference)
• NIST Chemistry Reference: 1beta-Hydroxyalantolactone(68776-47-6)
• EPA Substance Registry System: 1beta-Hydroxyalantolactone(68776-47-6)

Safety Data

• Hazardous Substances Data: 68776-47-6(Hazardous Substances Data)

Usage

Description

1beta-Hydroxyalantolactone is a naturally occurring sesquiterpene lactone derived from plants such as Inula helenium. It exhibits a range of pharmacological activities, including anti-inflammatory, anti-cancer, and anti-microbial properties, making it a promising candidate for therapeutic applications.

Uses

Used in Pharmaceutical Industry:
1beta-Hydroxyalantolactone is used as an anti-inflammatory agent for its ability to inhibit the production of inflammatory mediators such as nitric oxide and prostaglandin E2. This property makes it a potential treatment for various inflammatory conditions.
1beta-Hydroxyalantolactone is also used as an anti-cancer agent, particularly effective against various cancer cell lines, including breast, lung, and prostate cancer cells. Its anti-cancer properties stem from its ability to inhibit cancer cell growth and proliferation.
In addition to its direct anti-cancer effects, 1beta-Hydroxyalantolactone is used in combination therapies to enhance the efficacy of conventional chemotherapeutic drugs, potentially improving treatment outcomes for cancer patients.
Used in Microbiology and Infectious Disease Management:
1beta-Hydroxyalantolactone is used as an anti-microbial agent due to its activity against several bacterial strains. This makes it a potential candidate for the development of new antibiotics or as a complementary treatment in managing bacterial infections.
Overall, 1beta-Hydroxyalantolactone's diverse pharmacological activities position it as a versatile compound with potential applications in various medical and therapeutic fields.