68779-67-9

Basic information

• Product Name: vindeburnol
• Synonyms: RU24722;RU-24722;RU 24722;20,21-Dinoreburnamenin-14-ol, 14,15-dihydro-, (3α,14β)-(±)-;(3β,14α,16α)-(+/-)-14,15-dihydro-20,21-dinoreburnamenin-14-ol
• CAS NO: 68779-67-9
• Molecular Formula: C17H20N2O
• Molecular Weight: 268.358
• Mol File: 68779-67-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 482.5°Cat760mmHg
• Flash Point: 245.6°C
• Appearance: /
• Density: 1.46g/cm³
• PKA: 14.28±0.20(Predicted)
• CAS DataBase Reference: vindeburnol(CAS DataBase Reference)
• NIST Chemistry Reference: vindeburnol(68779-67-9)
• EPA Substance Registry System: vindeburnol(68779-67-9)

Safety Data

• Hazardous Substances Data: 68779-67-9(Hazardous Substances Data)

Upstream product

• 96184-81-5 (+/-)-cyclohexanone-4-carboxaldehyde 
• 132452-43-8 4-<(phenylmethoxy)methyl>cyclohexanone 
• 38580-68-6 4-hydroxymethyl-cyclohexanone 
• 34963-16-1 (+/-)-(3α,16β)-desethyleburnamonine 

Relevant articles and documents

Stereoselective total synthesis of (±)-vindeburnol and (±)-16-epi-vindeburnol

A concise stereoselective total synthesis of (±)-vindeburnol and its epimer (±)-16-epi-vindeburnol is presented. This synthetic work features the utilization of Baeyer-Villiger oxidation to install different types of lactone substrate, and a sequence of a

Total synthesis of (±)-deethyleburnamonine and vindeburnol (RU 24722) with the corresponding nitriles as starting material

Cyclisation occurred during base treatment of cis-nitrile (5). The resulting new imine (6) was converted into the therapeutically important deethyleburnamonine (4). Total synthesis of vindeburnol (RU 24722) (3), another important drug, was achieved in one step starting from the trans- nitrile (9).