68787-54-2Relevant articles and documents
Synthesis of New Condensed Pyrimidine Systems: Reactions of Heterocyclic Amines with Acetylenic Esters
Sahu, J. K.,Dehuri, S. N.,Naik, S.,Nayak, A.
, p. 117 - 120 (2007/10/02)
Several hitherto unreported 1,3,4-oxa/thiadiazolopyrimidin-7-ones (1 and 2) and thiazolopyrimidin-7-ones (3) have been synthesised by the reaction of 2-amino-1,3,4-oxa/thiadiazoles and 2-amino-4-arylthiazoles respectively with ethyl phenylpropiolate.The reaction of these amines with diethyl acetylenedicarboxylate furnishes the 7-oxo-5-carbethoxy derivatives (8-10).A similar reaction of 2-aminobenzothiazole with diethyl acetylenedicarboxylate affords 4-carbethoxypyrimidobenzothiazol-2(H)-one (7).To assign the structures of the 7-oxo derivatives the isomeric 5-oxo-7-carbethoxy derivatives (14) have also been synthesised by an unambiguous route.
Studies on Reactive Intermediates. Part I. An Approach to the Synthesis of 2-Phenyl-7-carbethoxy-5H-1,3,4-thiadiazolopyrimidin-5-one
Daneshtalab, M.,Motamedi, K.
, p. 785 - 787 (2007/10/02)
2-Phenyltetrazolo-1,3,4-thiadiazole (4), in its azido form, reacted with diethyl fumarate and diethyl maleate to give 2-phenyl-7-carbethoxy-5H-1,3,4-thiadiazolopyrimidin-5-one (5).To assign the structure of compound 5, 2-phenyl-5-carbethoxy-
